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  • 301035 - [Hydroxy(tosyloxy)iodo]benzene

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[Hydroxy(tosyloxy)iodo]benzene

301035 -

96%

DOWNLOAD MSDS (PDF)

Synonym: HTIB, Hydroxy(4-methylbenzenesulfonato-O)phenyliodine, Hydroxy(phenyl)iodo tosylate, Iodosobenzene-I-mono-p-toluenesulfonate, Koser’s reagent, NSC 294176, Phenyliodosyl hydroxide tosylate, [Hydroxy(4-toluenesulfonato)iodo]benzene

  • CAS Number: 27126-76-7

  • Linear Formula: CH3C6H4SO3I(OH)C6H5

  • Molecular Weight: 392.21

  • Beilstein Registry Number: 2150074

  • MDL number: MFCD00011547

  • PubChem Substance ID: 24858159

[Hydroxy(tosyloxy)iodo]benzene 96%
#

Properties

Related CategoriesHypervalent Iodine, Oxidation, Synthetic Reagents
assay96%
mp131-137 °C(lit.)

Description

Application

Widely used oxidant in the synthesis of various organic compounds.9

Reactant for:
• Ligand-free palladium-catalyzed Heck-type coupling reactions1
• Preparation of carbodiimides via dehydrosulfurization of thioureas2
• Preparation of nitriles by oxidative conversion of alcohols, aldehydes, and amines3
• Preparation of substituted anilines via aromatic aldoxime reaction4
• Preparation of tetrahydrofurans by oxidative cyclization of homoallylic alcohols5
• Preparation of isoxazoline N-Oxides from ß-hydroxyketoximes via oxidative N-O coupling6
• Ring expansion in synthesis of aminopeptidase inhibitors7
• Oxidation and protonation reactions in acidic conditions8

Packaging

5, 25 g in glass btl

Price and Availability

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Documents

Certificate of Analysis

FT-IR Condensed Phase
FT-IR Raman
FT-NMR
Structure Search
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Safety Information

SymbolGHS07  GHS07
Signal wordWarning
Hazard statementsH315-H319
Precautionary statementsP305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Gloves
Hazard CodesXi
Risk Statements36/38
Safety Statements26-36
WGK Germany3
Technical information & documentation associated with this product is available in the Safety & Documentation tab.

References

1. Qu, X.; et al. Adv. Syn. Catalysis 353, 1061, (2011)

2. Zhu, C.; et al. Synthesis, 711, (2011)

3. Zhu, C.; et al. Synthesis, 4235, (2010)

4. Ghosh, H.; et al. ARKIVOC, 209, (2011)

5. Vasconcelos, R. S.; et al. J. Org. Chem. 76, 1499, (2011)

6. Raihan, M. J.; et al. J. Org. Chem. 76, 424, (2011)

7. Roux, L.; et al. Tetrahedron 66, 8722, (2010)

8. Lin, Z.-P.; et al. Tetrahedron Lett. 51, 5996, (2010)

9. Kumar, R. Synlett, 2764, (2007)

Merck 14,5321

Fieser 14,179 / Fieser 16,179 / Fieser 17,150

Corp MSDS 1 (1), 1964:C / FT-IR 2 (2), 3266:C / FT-NMR 1 (2), 1615:A / RegBook 1 (2), 2223:H / Structure Index 1, 349:B:4


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